Research Paper Volume 14, Issue 15 pp 6316—6337
SAAL1, a novel oncogene, is associated with prognosis and immunotherapy in multiple types of cancer
Figure 12. SAAL1 silencing inhibits proliferation, migration, and invasion and downregulates PD-L1 expression in lung cancer cells. A549 cells were transfected with control or SAAL1-targeting siRNAs (siRNA1 and siRNA2). (A) EdU and CCK-8 proliferation assay results. (B) Transwell migration and invasion assay results. (C) Western blotting and RT-qPCR analysis of SAAL1 and PD-L1 expression. GAPDH was used as the loading control. *P<0.05, **P<0.01 vs. Con group.