Research Paper Volume 14, Issue 16 pp 6537—6553

Alterations of gut viral signals in atrial fibrillation: complex linkage with gut bacteriome

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Figure 4. Virus-bacteria co-occurrence networks. Virus-bacteria co-occurrence networks for non-AF controls (A) and AF patients (B). The nodes are viruses and bacterial species. Purple ellipses and blue rectangles represent bacterial species and viruses, respectively. Edges represent positive (orange) and negative (grey) associations of viruses with bacterial organisms at the species level. Nodes denote distinct bacterial organisms or viruses, with their sizes being proportional to mean relative abundances. The cutoff Spearman correlation coefficient and the adjusted p-value were |0.7| and 0.05, respectively. Degrees of distribution of virus-bacteria co-occurrence networks (C). Comparison of the alteration levels of the virus-bacteria co-occurrence networks based on the rates of removed modes (D). Degrees of viral nodes in virus-bacteria co-occurrence networks (E).