An aqueous extract of the brown alga <i>Eisenia bicyclis</i> extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis

Navid Tahanzadeh; Mirjam Knop; Yvonne Seidler; Sebastian Dirndorfer; Kai L&#xFC;rsen; Iris Bruchhaus; Roman Lang; Gerald Rimbach; Thomas Roeder

doi:doi:10.18632/aging.204218

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Research Paper Volume 14, Issue 16 pp 6427—6448

An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis

Figure 6. Untargeted HPLC-MS analysis of algae extracts. Principal component analysis (PCA) (A) of algae extracts measured using the ESI+ and ESI- acquisition mode. Underlying peak areas are log10 transformed and pareto-scaled. (B, C) LC-ToF-MS intensities of 7-phloroeckol (B) and caffeic acid quinone (C). Intensities are displayed as the mean of triplicate injections (duplicate injections for Saccorhiza).