Figure 4.PDCD10 alters the protein expression level of CXCR2 and regulates the activation of downstream AKT/ERK signal pathways. (A, B) Western blotting was used to detect the expression level of CXCR2 and phosphorylation level of AKT, ERK1/2 and STAT3 in Att-20 cells after PDCD10 silencing or overexpression. Band intensities were quantified and normalized to GAPDH. * P < 0.05. (C, D) In TtT/GF cells, western blotting was performed to examine the expression level of CXCR2 and phosphorylation level of AKT, ERK1/2 and STAT3 after PDCD10 silencing or overexpression. Band intensities were quantified and normalized to GAPDH. * P < 0.05.
