Research Paper Volume 14, Issue 14 pp 5878—5894

Figure 7. miR-5701 inhibited GC proliferation and metastasis in vivo. (A) SGC-7901 cells were infected with LV-miR-5701 or LV-ctrl and inoculated into groin subcutaneous tissue of nude mice, left for LV-ctrl, right for LV-miR-5701. (B) Tumors were measured by in vivo bioluminescence image. (C) Mice were sacrificed and tumors were isolated. (D) miR-5701 expressions in tumors were detected by qRT-PCR. (E–G) SGC-7901 cells were infected with LV-miR-5701 or LV-ctrl and injected into tail vein of nude mice, tumor metastasis in lung was detected by HE staining and by in vivo bioluminescence imaging.