Research Paper Volume 14, Issue 14 pp 5838—5854

Overexpression of 14-3-3ζ primes disease recurrence, metastasis and resistance to chemotherapy by inducing epithelial-mesenchymal transition in NSCLC

class="figure-viewer-img"

Figure 2. Expression of 14-3-3ζ protein in surgical resected NSCLC samples. (A) Representative IHC staining of 14-3-3ζ protein in NSCLC tissues at different clinical stage. The IHC score of 14-3-3ζ in each group was analyzed (*P < 0.05 vs. stage IIA, ***P < 0.01 vs. stage IIA). Scale bar = 200 μm. (B) Representative IHC images of 14-3-3ζ protein in patients without (upper panel) and with (lower panel) disease recurrence. Scale bar = 200 μm.