Editorial Volume 14, Issue 14 pp 5614—5616
Nutlin-3a for age-related macular degeneration
Figure 1. Elimination of senescent cells improves retinal regeneration. The MDM2-p53 inhibitor, Nutlin-3a, eliminated senescent retinal pigment epithelial cells and decreased the levels of inflammatory cytokine proteins, ameliorating retinal degeneration in mouse models.