Research Paper Volume 14, Issue 14 pp 5783—5799

The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma

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Figure 6. miR-590-3p/CFHR3/p-STAT3/p53 pathway is required for HCC patient poor prognosis. (AD) The OS or DFS curves are based on CFHR3 transcript levels (A, B) or miR-590-3p levels (C, D) in HCC subgroups with STAT3 high expression. (EH) The OS or DFS curves are based on CFHR3 transcript levels (E, F) and miR-590-3p levels (G, H) in HCC subgroups with STAT3 low expression. (I) A schematic overview of the signaling axis of miR-590-3p/CFHR3/p-STAT3/p53.