Figure 6. miR-590-3p/CFHR3/p-STAT3/p53 pathway is required for HCC patient poor prognosis. (A–D) The OS or DFS curves are based on CFHR3 transcript levels (A, B) or miR-590-3p levels (C, D) in HCC subgroups with STAT3 high expression. (E–H) The OS or DFS curves are based on CFHR3 transcript levels (E, F) and miR-590-3p levels (G, H) in HCC subgroups with STAT3 low expression. (I) A schematic overview of the signaling axis of miR-590-3p/CFHR3/p-STAT3/p53.