Research Paper Volume 14, Issue 18 pp 7348—7363

Figure 1. Flow chart of the study. The RNA-seq data for GBM were obtained from TCGA and m6A-related immune lncRNAs were intersected among immune genes, 19 m6A genes, and 494 differently-expressed lncRNAs. Adding the clinical information, univariate and multivariate COX regression and LASSO were applied to identify one m6A-regulated ir-lncRNA which is correlated with the survival status of GBM patients. Then, the ir-lncRNAs were analyzed for immune status, immune checkpoint inhibitors, and chemical sensitivity for GBM.