Research Paper Volume 14, Issue 13 pp 5511—5522

Detachment stress mediated bioenergetic switch of malignant melanoma cells into anti-Warburg phenotype

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Figure 4. Detachment stress increased (A) the superoxide and ROS production, and (B) HIF-1α expression in melanoma A375 cells. Data were mean ±S.D. (n=3); **, p < 0.01.