Research Paper Volume 14, Issue 13 pp 5478—5492

Computational study on novel natural compound inhibitor targeting IDH1_R132H

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Figure 4. The inter-molecular interaction of the predicted binding modes of (A) ZINC000004098459 to IDH1_R132H; (B) ZINC000049872393 to IDH1_R132H (C) Vorasidenib to IDH1_R132H (D) Ivosidenib to IDH1_R132H.