Research Paper Volume 14, Issue 11 pp 4839—4857
Identification of biomarkers for immunotherapy response in prostate cancer and potential drugs to alleviate immunosuppression
Figure 8. Drug candidates were filtered from the LINCS database, which were predicted to contribute to immunotherapy. (A) Nine drugs in PC3 and two drugs in LNCaP cells were significantly regulated hub genes computed by Gene Set Enrichment Analysis (GSEA). The GSEA plots of resveratrol (B) and radicicol (C), the most significantly effective drugs for the PC3 and LNCaP cell lines, respectively, show their regulation of hub genes.