Figure 3 — NEAT1 variant 1 weakens the genome-wide effect of miR-3122 on blocking H3K79me3 in bladder cancer

Research Paper|Volume 14, Issue 11|pp. 4819–4826

NEAT1 variant 1 weakens the genome-wide effect of miR-3122 on blocking H3K79me3 in bladder cancer

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Figure 3.miR-3122 affects global H3K79me3 in BC cells. Dot plot assay show the global levels of H3K4me3, H3K9me3, H3K27me3 and H3K79me3 in T24 (A), BIU-87 (B) and EJ-1 (C) cells with ectopic miR-3122 and NEAT1.1 over-expression. The expression of H3K79 methyltransferase DOT1L in T24 (D), BIU-87 (E) and EJ-1 (F) cells with ectopic miR-3122 and NEAT1.1 over-expression.