Research Paper Volume 14, Issue 10 pp 4402—4424

Intra-tumoral angiogenesis correlates with immune features and prognosis in glioma

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Figure 4. The angiogenesis score reflected the immune characteristics of glioma. (A, B) In the TCGA (A) and CGGA (B) datasets, with the increase of the angiogenesis pathway score, the purity of glioma was significantly reduced, the immune score was significantly increased, and the enrichment degree of most immune cells was also significantly increased. (C, D) The expression level of most immune checkpoints increased significantly as the angiogenesis score increased in the TCGA (C) and CGGA (D) cohorts.