Research Paper Volume 14, Issue 10 pp 4402—4424
Intra-tumoral angiogenesis correlates with immune features and prognosis in glioma
Figure 3. Angiogenesis score distinguished the malignant subtypes of glioma. (A) The angiogenesis score was significantly correlated with WHO grade of glioma in the TCGA cohorts. (B) Higher angiogenesis score enriched in IDH-wildtype gliomas than in IDH-mutant gliomas in the TCGA cohorts. (C) Higher angiogenesis score in 1p19q non-codeleted gliomas than in 1p19q codeleted gliomas in the TCGA cohorts. (D) MGMT promoter unmethylated gliomas had a significantly higher angiogenesis score than MGMT promoter methylated gliomas in the TCGA cohorts. (E) The angiogenesis score was significantly correlated with WHO grade of glioma in the CGGA cohorts. (F) Higher angiogenesis score enriched in IDH-wildtype gliomas than in IDH-mutant gliomas in the CGGA cohorts. (G) Higher angiogenesis score in 1p19q non-codeleted gliomas than in 1p19q codeleted gliomas in the CGGA cohorts. (H) MGMT promoter unmethylated gliomas had a significantly higher angiogenesis score than MGMT promoter methylated gliomas in the CGGA cohorts.