Figure 4. The effects of exercise training on the cardiac fibrotic downstream pathway. (A) The representative protein quantification of TIMP1, TIMP2, MMP2, MMP9, uPA and Collagen I extracted from the left ventricles were measured by Western blotting analysis; (B) Bars represent the densitometric analysis of MMP2/TIMP2, MMP9/TIMP1, uPA and Collagen I. Data are expressed as the mean values ± SD (n = 8 in each group). *p < 0.05, **p < 0.01 vs. the WKY group. ##p < 0.01 the SHR group vs. SHR-EX group.