Research Paper Volume 14, Issue 10 pp 4390—4401
Exercise intervention prevents early aged hypertension-caused cardiac dysfunction through inhibition of cardiac fibrosis
Figure 3. Effects of exercise training on the cardiac fibrotic upstream pathway. (A) The representative protein quantification of LOX-2, TGF-β, CTGF and p-Smad2/3 extracted from the left ventricles were measured by Western blotting analysis; (B) Bars represent the densitometric analysis of LOX-2, TGF-β, CTGF and p-Smad2/3. Data are expressed as the mean values ± SD (n = 8 in each group). *p < 0.05, **p < 0.01 vs. the WKY group. ##p < 0.01 the SHR group vs. SHR-EX group.