Research Paper Volume 15, Issue 16 pp 8518—8527

miR-153-3p suppresses the differentiation and proliferation of neural stem cells via targeting GPR55

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Figure 5. miR-153-3p induces proinflammatory cytokine release. (A) The concentration levels of TNF-α, IL-1β and IL-6 were upregulated in NSCs after treatment with the miR-153-3p mimic. (B) Knockdown of miR-153-3p suppressed the concentration levels of TNF-α, IL-1β and IL-6 in NSCs. **p<0.01 and ***p<0.001. Error bars represent the s.d. of relative experiment from n=3 replicates.