Research Paper Volume 14, Issue 7 pp 3129—3142

miRNA-29 aggravates myocardial infarction via inhibiting the PI3K/mTOR/HIF1α/VEGF pathway

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Figure 4. Effects of miR-29 on cardiac structure and function in vivo. (A) Echocardiography results showed that LVEF, FS (%) and LVAW (diastolic and systolic) were gradually decreased in miR-29 inhibition group and model group from 0 d to 28 d, respectively, and these diseases were more significant in model group than those in miR-29 inhibition group. (B) Result is displayed in terms of statistical chart. Data were presented as mean ± SE (*P<0.05, **P<0.01). LVEF: left ventricular ejection fraction; LVAW; d: left ventricular anterior wall; diastolic; LVAW; s: left ventricular anterior wall; systolic; FS%: fractional shortening.