E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice

Laura E. Pascal; Taro Igarashi; Shinsuke Mizoguchi; Wei Chen; Lora H. Rigatti; Caroline G. Madigan; Rajiv Dhir; Wade Bushman; Donald B. DeFranco; Naoki Yoshimura; Zhou Wang

doi:doi:10.18632/aging.203994

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Research Paper Volume 14, Issue 7 pp 2945—2965

E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice

Figure 6. Impact of prostate-specific E-cadherin deficiency on bladder histology in mice analyzed at 24 months of age. H&E staining of transverse sections of bladder and bladder neck from Control and Cdh1^+/- mice at 24 months of age. Abbreviations: BL: bladder lumen; UL: urethra lumen; IUO: Internal urethral orifice. Lymphoid aggregates (shown in Cdh1^+/- image) were observed in both control and Cdh1^+/- mice. Original magnification, 5×, scale bars indicate 400 μm in 5×.