Research Paper Volume 14, Issue 7 pp 2945—2965
E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice
Figure 3. Impact of aging on proliferation in the murine prostate. (A) Quantification of Ki-67+ epithelial, and (B) stromal cells in the lobes of the prostate from control mice at 6 and 24 months of age. Abbreviations: vp: ventral prostate; lp: lateral prostate; dp: dorsal prostate; ap: anterior prostate. (C) Ki-67 immunostaining (brown) in dorsal lobes from control mice at 6 and 24 months of age. Black arrow indicates Ki-67+ stromal cell in control mice at 6 months of age. Original magnification, 40×, inset 40×. Data represent mean ± S.D, number of mice in each group in parentheses. Lobes which had been washed away during staining process were not quantified. *p < 0.05, **p < 0.01. Scale bars indicate 50 μm in 40×.