Research Paper
RBM3 promotes aerobic glycolysis and chemoresistance in renal clear cell carcinoma cells through regulating HK2
Figure 5. RBM3 regulated the chemoresistance of ccRCC cells by HK2 in vitro. (A) Cells invasion of the 769-P and OSRC-2 cells exposed to 5-FU. Representative images were shown on the left. Bar graphs were mean ± SD. n = 5. (B) Colony formation of the 769-P and OSRC-2 cells exposed to 5-FU, n = 3. (C) The effect of RBM3 on cell apoptosis was abolished by HK2 siRNA or 2-DG. (D) MTT was used to measure cell viability, n = 10. *p < 0.05 vs. EV; #p < 0.05 vs. RBM3.