Research Paper
RBM3 promotes aerobic glycolysis and chemoresistance in renal clear cell carcinoma cells through regulating HK2
Figure 1. RBM3 level in ccRCC. (A) The expression of RBM3 was predicted based on the Oncomine database. (B) The expression of RBM3 was predicted based on the GEPIA database. (C) The expression of RBM3 in carcinoma and paracancerous tissues of 30 patients with ccRCC was detected by qRT-PCR. n = 30. (D) RBM3 protein in ccRCC and paracancerous tissues was detected using western blot. Representative image was shown on the left. Quantification data represented mean ± SD (normalized to adjacent tissue). n = 6. (E) Immunohistochemistry was used to detect RBM3 protein in renal cell carcinoma and paracancerous tissues. (F) The expression of RBM3 was analyzed by qPCR in the different stage of the patients. (G) The correlation of RBM3 expression with overall survival and disease-free survival of the patients was analyzed. Representative image was shown. *p < 0.05, **p < 0.01 vs. normal.