Figure 5. CIRCRBM33 regulates tumor growth via targeting CBX7. (A) Ki-67 staining was used to detect the cell proliferation; (B) Cell cycle determined by flow cytometry analysis. (C) The cell proliferation was detected by clone formation assay. (D) The cell invasion was measured by Transwell assay. (E) The cell apoptosis was determined by TUNEL assay. Data are presented as mean ± SEM. Statistic significant differences were indicated: ** P < 0.01 vs. si-NC; #P <0.05 vs.si-circRBM33.