Research Paper Volume 14, Issue 5 pp 2194—2209

Tonsil mesenchymal stem cells-derived extracellular vesicles prevent submandibular gland dysfunction in ovariectomized rats

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Figure 3. Serum estradiol levels and expression of estrogen receptor β. Serum estradiol levels were lower in the OVX group than in the SHAM group. Exosome treatment did not affect the serum estradiol levels (A). Quantitative polymerase chain reaction analysis of genes encoding representative estrogen receptor β in the submandibular gland. The expression of ERβI and ERβII did not change between the groups (B). One-way ANOVA test; ***p < 0.001 vs. SHAM.