Research Paper Volume 14, Issue 5 pp 2081—2100

Figure 5. Gene-gene interaction networks among selected genes constructed by GeneMANIA. A gene-gene network was constructed with the search tool for the retrieval of interacting genes available in GeneMANIA annotation information for selected 5 genes, including physical interaction, genetic interaction, co-expression and shared pathways and protein structure domain. The central black nodes denote 5 selected genes used as an “INPUT”, and peripheral nodes denote gene interactions with the black nodes. The network also contains 20 normal human genes. The size of the circles indicates the degree of interaction.