Research Paper Volume 14, Issue 4 pp 1983—2003

Pseudogene AK4P1 promotes pancreatic ductal adenocarcinoma progression through relieving miR-375-mediated YAP1 degradation

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Figure 6. The distribution and expression of four hub genes (CTNNB1, YAP1, PSEN1, and SP1) in PDAC. (A) The distribution of four hub genes (CTNNB1, YAP1, PSEN1, and SP1) in different cell types of human pancreas was confirmed by scRNA-seq. (B) The expression level of four hub genes (CTNNB1, YAP1, PSEN1, and SP1) in different cell types of human pancreas were determined by scRNA-seq. (C) The protein levels of four hub genes (CTNNB1, YAP1, PSEN1, and SP1) expression in PDAC and normal pancreas tissues were determined by immunohistochemical staining data from HPA. scale bar, 100 mm.