Figure 8.circSHPRH knockdown activates the Wnt/β-catenin signaling pathway by regulating BARX2. (A, B) Relative expression of BARX2, β-catenin and c-MYC in T24 and UM-UC-3 cells transfected with vector or BARX2 plasmid. (C–F) Rescue assays indicated that the promoting effect of circSHPRH knockdown on c-MYC and nuclear β-catenin expression was partially diminished by BARX2 overexpression in T24 (C, D) and UM-UC-3 cells (E, F).*P<0.05, **P<0.01.
