Figure 2.Distinct level of cellular apoptosis in colon cancer tissue samples with distinct genotypes and methylation levels of KCNQ1OT1 promoters (scale bar: 25 μm). (A) Increased expression of ATG4B protein in group A: carrier of allele 10 + methylated, B: carrier of allele 10 + non-methylated, C: non-carrier of allele 10 + methylated, D: non-carrier of allele 10 + non-methylated. (B) Decreased apoptosis in group A: carrier of allele 10 + methylated, B: carrier of allele 10 + non-methylated, C non-carrier of allele 10 + methylated, D: non-carrier of allele 10 + non-methylated.
