Figure 2. Comparison of different dALFF values between the DON patients and HCs. Spatial patterns of dALFF variance were observed in DON patients. The mean dALFF variance maps within DON patients (A). Compared with HCs, patients with DON showed increased MRG_R dALFF value and decreased PreC_R dALFF value. Representative distributions of them in the coronal, sagittal and transverse positions (B) and three-dimensional distributions (C). Two-sample t-test was used to compare dALFF values between two groups. The mean values of altered dALFF between the DON patients and HCs (D). * represented to P< 0.01. The warm color areas denote higher values, and the cool color areas denote lower values in two groups. Abbreviations: dALFF, dynamic amplitude of low-frequency fluctuation; DON, diabetic optic neuropathy; HCs, healthy controls; MFG, middle frontal gyrus; PreC, precuneus; R, right; L, left.