Research Paper Volume 14, Issue 2 pp 800—810

The interaction protein of SORBS2 in myocardial tissue to find out the pathogenic mechanism of LVNC disease

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Figure 5. Expression of SORBS2 in hESC-CMs transfected with HBLV-h-SORBS2 was higher compared with the control groups. (A) Cardiomyocytes transfected with lentivirus. (B) Representative images of SORBS2 in hESC-CMs transfected with empty virus (control) and HBLV-h-SORBS2 (SORBS2-OE). (C) Western blotting detection of the expression levels of SORBS2 in overexpression group and control group. The protein level of SORBS2 was normalized to GAPDH for each sample. Statistical analysis of the expression of SORBS2 in hESC-CMs transfected with empty virus (control) and HBLV-h-SORBS2 (SORBS2-OE) (n =3 per group, * p < 0.05; Student's t-test). Data are shown as the mean ± SEM.