COVID-19 Research Paper Volume 14, Issue 1 pp 73—108
Decreased TMPRSS2 expression by SARS-CoV-2 predicts the poor prognosis of lung cancer patients through metabolic pathways and immune infiltration
Figure 11. The alteration of TMPRSS2 expression during SARS-CoV-2 infection. (A) The change in TMPRSS2 expression in the GSE45042 (mock, n = 15; SARS-CoV, n = 17), GSE33267 (mock, n = 33; SARS-CoV, n = 33), GSE17962 (mock, n = 33; SARS-CoV, n = 27; H1N1, n = 21), and GSE156544 (mock, n = 2; SARS-CoV2, n = 2) datasets. (B) TMPRSS2 protein levels in lung cancer tissues (n = 111) and normal tissues (n = 111) from the UALCAN database. (C) TMPRSS2 protein level in lung cancer and normal tissues from the HPA database. The staining was quantified (normal lung tissue, n = 3; lung cancer, n = 7). *p < 0.05, **p < 0.01, ***p < 0.001.