Research Paper Volume 14, Issue 3 pp 1265—1279
Hesperidin suppresses ERS-induced inflammation in the pathogenesis of non-alcoholic fatty liver disease
Figure 4. HSP could attenuate ERS-induced inflammation in the liver. (A) Immunofluorescence staining was performed to examine the expression of GRP94 in liver tissues. (B) Western blotting analysis was performed to examine the expression of GRP94, ATF6, ATF4, p-PERK, and p-IRE1α in liver tissues. Data were presented as mean ± SEM. **P < 0.05, HFD + HSP vs. HFD; &&P < 0.05, ND + HSP vs. ND. (C) Western blotting analysis was performed to examine the expression of IL-1β, IL-6, and TNF-α. Data were presented as mean ± SEM. **P < 0.05, HFD + HSP vs. HFD; &&P < 0.05, ND + HSP vs. ND.