Figure 6 — Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies

Research Paper|Volume 14, Issue 1|pp. 410–429

Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies

Back to articleFigure 6(6 of 7)

100%

Figure 6.Role of miR-135b in the regulation of FOXO1 and related proteins. After transfection of inhibitor mir-135b, ECs were subjected to ESWT with 0.05 mJ/mm², 1000 shots followed by DEX with 180 μM. (A–J) Immunoblotting and statistical graph of FOXO1, Cyclin D1, Bim, Bcl2, Bax, cleaved Caspase-3, MMP2, MMP9 (N-terminal), Cyclin E1, and VEGFA. n=3 ^**P < .01, ^***P < .001.