Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: <i>in vitro</i> and <i>in vivo</i> studies

Xinjie Wu; Yanlei Wang; Xiaoyu Fan; Xin Xu; Wei Sun

doi:doi:10.18632/aging.203816

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Research Paper Volume 14, Issue 1 pp 410—429

Extracorporeal shockwave relieves endothelial injury and dysfunction in steroid-induced osteonecrosis of the femoral head via miR-135b targeting FOXO1: in vitro and in vivo studies

Figure 1. Effect of ESWT on proliferation, angiogenesis, and apoptosis in steroid-induced ONFH in rats. (A) blood supply assessed by micro-CT scanning; (B) CD31 staining in the femoral head; (C) Ki-67 staining in the femoral head; (D) TUNEL staining in the femoral head. (magnification, ×20) n=6 ^**P < .01, ^***P < .001.