Figure 6. Functional analysis of mRNA in CRC metastasis. GO enrichment showed upregulated (A) and downregulated (B) mRNAs in CRC metastasis-associated biological processes. KEGG pathway analysis showed upregulated (C) and downregulated (D) CRC metastasis-associated signaling pathways. Hallmark gene sets analysis showed upregulated (E) and downregulated (F) expression in CRC metastasis-associated immunologic signatures.