Research Paper Volume 13, Issue 24 pp 25778—25798
PKMYT1, exacerbating the progression of clear cell renal cell carcinoma, is implied as a biomarker for the diagnosis and prognosis
Figure 2. Differential expression analysis of WEE family kinases. Expression levels of WEE1 (A) and WEE2 (B) were down-regulated in tumors (normal (n = 72); tumor (n = 533)), while PKMYT1 (C) was up-regulated in tumors compared with normal tissue samples in the TCGA dataset. A consistent result for WEE1 (D) and WEE2 (E) were also obtained for paired normal and tumor samples (normal (n = 72); tumor (n = 72)), while PKMYT1 was up-regulated in tumors (F). Expression levels of WEE1 and WEE2 exhibited no significant difference in the GSE36895 (G, H). PKMYT1 was up-regulated in tumors in the GSE36895 (I). Expression levels of WEE1 and WEE2 exhibited no significant difference in the GSE76351 (J, K). PKMYT1 was up-regulated in tumors in the GSE36895 (L).