Research Paper Volume 13, Issue 23 pp 25325—25341

Artesunate treatment ameliorates ultraviolet irradiation-driven skin photoaging via increasing β-catenin expression

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Figure 6. The effects of Art treatment and silencing β-catenin expression on UVB-irradiated skin photoaging of mice. (A, B) Clinical and dermoscopic observations of the back skin of mice in control group, UV + sh-NC group, UV + sh-β-catenin group, UV + sh-NC + Art group and UV + sh-β-catenin + Art group. (C) Quantification of the number of stains in skin tissue of mice from each group. (DF) Western blot of the expression of β-catenin and p16INK4a in skin tissues of mice. *p<0.05; **p<0.01; ***p<0.001; ****p<0.0001.