Research Paper Volume 13, Issue 21 pp 24464—24475

Propofol suppresses the growth and invasion of cervical carcinoma cells by inhibiting MIR155HG

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Figure 1. Propofol reduces cervical cancer cell growth and invasion. (A) Chemical structure of propofol. (B) CCK-8 proliferation assay of Caski and SiHa cells treated with different concentrations of propofol for 24 hours, 48 hours or 72 hours. (C) Colony formation assay of Caski and SiHa cells treated with propofol (30~80 μM). (D) Transwell invasion assays showed that propofol decreased the invasion ability of Caski and SiHa cells. *P<0.05, **P<0.01 compared with control.