Research Paper Volume 13, Issue 21 pp 23953—23980

UBB+1 reduces amyloid-β cytotoxicity by activation of autophagy in yeast

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Figure 2. Low UBB+1 expression activates autophagy at the transcript level. (A) Schematic overview of autophagosome formation. (B) Fold changes in the expression of ATG genes encoding for autophagosome formation. Abbreviation: PI3K, phosphatidylinositol 3-kinase. (C) Fold changes in the expression of genes encoding different modes of autophagy. All comparison is between L-UBB+1 strain and control strain during EX and D6 phases (adj-p < 0.05).