Research Paper Volume 13, Issue 21 pp 24271—24289

Immunological and clinical immunotherapy implications of NLRP3 mutations in melanoma

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Figure 1. The mutational patterns of NLR family members and genome maintenance genes. (A) TMB stratified by synonymous and non-synonymous mutations for each patient. (B) Waterfall plot for NLR family members and genome maintenance genes. (C) Association of NLRP3 mutations with BRCA1/2, TP53, POLE, and MMR genes mutations.