Figure 6 — Mutations in DNA damage response pathways as a potential biomarker for immune checkpoint blockade efficacy: evidence from a seven-cancer immunotherapy cohort

Research Paper|Volume 13, Issue 21|pp. 24136–24154

Mutations in DNA damage response pathways as a potential biomarker for immune checkpoint blockade efficacy: evidence from a seven-cancer immunotherapy cohort

Back to articleFigure 6(6 of 6)

100%

Figure 6.DDR mutations association with factors in the immune microenvironment. (A) Diverse infiltration abundance of 22 immune cells based on DDR mutational status; (B) Distinct expression of 33 immune checkpoints in patients with and without DDR mutations; (C) Distinct enrichment of 15 immune signatures in patients with and without DDR mutations. ^*P < 0.05; ^**P < 0.01; ^***P < 0.001.