Curcumol inhibits malignant biological behaviors and TMZ-resistance in glioma cells by inhibiting long noncoding RNA FOXD2-As1-promoted EZH2 activation

Xuyang Lv; Jiangchuan Sun; Linfeng Hu; Ying Qian; Chunlei Fan; Nan Tian

doi:doi:10.18632/aging.203662

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Research Paper Volume 13, Issue 21 pp 24101—24116

Curcumol inhibits malignant biological behaviors and TMZ-resistance in glioma cells by inhibiting long noncoding RNA FOXD2-As1-promoted EZH2 activation

Figure 4. Curcumol treatment down-regulated FOXD2-As1 expression. (A) The expression of FoxD2-As1 was detected in the normal human astrocytes (NHAs) and glioma cell lines. (B) The expression of FoxD2-As1 was detected in glioma cells treatment with curcumol for 24, 48, and 72 h. ^*P < 0.05, ^**P < 0.01.