Research Paper Volume 13, Issue 20 pp 23603—23619

Figure 8. iCRT3 significantly reversed the influence of resveratrol on apoptosis in vitro. (A) Influence of iCRT3 on the Wnt signaling related proteins expression through western blotting; (B) CRT3 significantly inhibited the protein expression of Wnt signaling related proteins; (C) iCRT3 significantly inhibited the mRNA expression of Wnt signaling related proteins; (D) The influence of iCRT3 on the apoptosis was investigated; (E) iCRT3 significantly reversed the influence of resveratrol on apoptosis in vitro; (F) iCRT3 significantly reversed the influence of resveratrol on cell proliferation in vitro; (G) Influence of iCRT3 on the protein expression of inflammatory factors through western blotting; (H) iCRT3 significantly reversed the influence of resveratrol on inflammatory factors expression. *P <0.05 compared with group control, #P <0.05 compared with group H₂O₂, + P <0.05 compared with group SCI+resveratrol. The experiments were repeated at least 3 independent times.