Research Paper

LINC01224 promotes gastric cancer development via miR-193a-5p/YES1 pathway

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Figure 1. The expression of LINC01224 is up-regulated in gastric cancer tissues and cells and is related to the prognosis of patients with gastric cancer. (A) Comparison of LINC01224 expression in gastric cancer tissues (red) and normal tissues (grey) from TCGA-STAD datasets and GTEx datasets. (B) Expression of LINC01224 in gastric cancer tissues (red) and adjacent tissues (grey) from TCGA Dataset. (C) Expression of LINC01224 in 27 pairs of gastric cancer tissues (red) and corresponding paracancerous tissues (blue) from TCGA datasets. (D) Expression of LINC01224 in 294 pairs of gastric cancer tissues and corresponding paracancerous tissues was detected by qRT-PCR. (E) Our cohort of gastric cancer patients was analyzed for postoperative survival based on LINC01224 expression by Kaplan-Meier survival analysis. (F) Expression of LINC01224 in gastric cancer cell lines (HGC-27, KATO III, SNU-1, AGS and NCI-N87) and normal gastric mucosal epithelial cell lines (GES-1) was detected by qRT-PCR.