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Figure 4
Figure 4.Forced expression of miR-491-5p remits the cell progression in stabled circ_CELF1 expression NSCLC cells. (A) CCK-8 assay was performed to detect the effect of miR-491-5p on overexpression of circ_CELF1 A549 and H1975 cells. n = 6, *P < 0.05. (B) The cell cycle was explored by flow cytometry on overexpression of circ_CELF1 A549 and H1975 cells after miR-491-5p transfection. n = 6, *P < 0.05. (C) The clone formation assay was performed on overexpression of circ_CELF1 A549 and H1975 cells. n = 5, *P < 0.05. (D) Wound healing assay was used to confirm the migration ability. n = 5, *P < 0.05. (E) The migration and invasion ability was explored by Transwell. n = 6, *P < 0.05, **P < 0.01.
Figure 4 — Circular RNA CELF1 drives immunosuppression and anti-PD1 therapy resistance in non-small cell lung cancer via the miR-491-5p/EGFR axis | Aging