Figure 3. Forest plot of the subgroup outcomes. (A) Pooled ORR of patients with visceral metastasis. (B) Pooled ORR of patients with lymph node only metastasis. (C) Pooled ORR of patients with the primary tumor in the upper tract. (D) Pooled ORR of patients with the primary tumor in the lower tract. The diamonds represent the pooled indexes. The line crossing the square represents the 95% CI. I2 indicates the heterogeneity in each subgroup meta-analysis. P demonstrates the significance of differences between the subgroups.