Research Paper Volume 13, Issue 16 pp 20218—20228
ERCC6L promotes cell growth and metastasis in gastric cancer through activating NF-κB signaling
Figure 6. NF-κB signal involved in ERCC6L-facilitated GC cell EMT, growth, migration, and invasion. (A) Western blot analysis of the levels of p-NF-κB p65, E-cadherin and N-cadherin in modified AGS cells treated with helenalin (15 μM, NF-κB signaling inhibitor). (B) Determination of cell proliferation ability followed by the treatment with helenalin by CCK-8 assay. (C) Determination of cell migration and invasion abilities followed by the treatment with helenalin by transwell assay. *P < 0.05.