Research Paper Volume 13, Issue 15 pp 19598—19613

Figure 3. (A) ZINC000013374324-mTORC1 complex. Schematic drawing of interactions between ligands and mTORC1, the surface of the binding area was added, blue represented positive charge, red represented negative charge, and ligands were shown in the sticks, the structure around the ligand-receptor junction was shown in thinner sticks. (B) ZINC000012495776 -mTORC1 complex. Schematic drawing of interactions between ligands and mTORC1, the surface of the binding area was added, blue represented positive charge, red represented negative charge, and ligands were shown in the sticks, the structure around the ligand-receptor junction was shown in thinner sticks. (C) Rapamycin-mTORC1 complex. Schematic drawing of interactions between ligands and mTORC1, the surface of the binding area was added, blue represented positive charge, red represented negative charge, and ligands were shown in the sticks, the structure around the ligand-receptor junction was shown in thinner sticks.