UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson’s disease mice after oral administration of Wen-Shen-Yang-Gan decoction

Guoxue Zhu; Wang Wang; Chang Chen; Lili Tang; Yan Liang; Zhennian Zhang; Yan Lu; Yang Zhao

doi:doi:10.18632/aging.203361

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Research Paper Volume 13, Issue 15 pp 19510—19528

UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson’s disease mice after oral administration of Wen-Shen-Yang-Gan decoction

Figure 6. PCA score plot of all analyzed samples in positive-ion (A) mode and negative-ion (B) mode with the statistical parameters; S-plot of OPLS-DA in positive-ion (C) mode and negative-ion (D) mode with the statistical parameters; VIP value plot in positive-ion (E) mode and negative-ion (F) mode.